Cancer Clinical Trial - Agenus C-800-01
Cancer
Status:
OpenClinicalTrials.gov:
NCT03860272CONDITION(S): Ovarian Cancer -TRIAL:Agenus C-800-01.
This study is an open-label, Phase 1, multicenter study to evaluate the safety, tolerability, PK, and PD profiles of a novel Fc-engineered IgG1 anti-CTLA-4 human monoclonal antibody (AGEN1181), and to assess the maximum tolerated dose (MTD) in subjects with advanced solid tumors. This study will also determine the RP2D of AGEN1181 monotherapy.